~ First a preliminary notice or announcement. In November we once again broke the record for both visits and page views (smashed the latter is more like it). We had more than 3,000 additional visits in November as our previous record of 53,500 visits set in October. As for page views, October’s record of 95,000 was smashed by an additional 17,000 page views.
Unfortunately, demands on my time have been increasing from several fronts, including the business that pays the rent. All this to say that while I sincerely appreciate the emails (and comments on the blog), please, please don’t be offended if I don’t get back to you. I’m getting dozens of emails per day now, many of them complex and with questions, and if I’m going to maintain a quality blog for all, I’ve got to set some limits somewhere. Also, some of you have good ideas for websites, forums, email lists and so on and I encourage you to pursue them — and I certainly don’t mind a mention from this blog. But it is very unlikely that I will be able to participate in any important way.
Look, I’m not saying don’t email me, but you’re gonna have to take your own chances about getting any kind of acknowledgement or response. And, for sure, I really like getting links to relevant news and studies and so forth and I’ll always endeavor, at minimum, to acknowledge your effort if I end up blogging about it.
~ Speaking of new forums, how about The Primal Tribe, a project of Philip Kafka. Here’s what Philip tells me about it.
Enter The Primal Tribe – an online community for people who pursue a natural, healthy, and caveman inspired existence. The Primal Tribe is a brand new forum for people who believe that when it came to diet, and activity levels, that the first people were also the right people. They might have eaten and moved as they did out of necessity, but we admire their living habits, and follow them out of choice.
The Primal Tribe is composed of healthy, strong, and devoted people – people whith determination and will power. It is for people who want to expand and introduce their knowledge of natural, primal living, and want to connect with others of the same mindset.
The community is young, and it is yours to form. Please register, look around, and introduce any topics of discussion that you might have.
The more the merrier. And, the more different approaches and variety, the larger the net that’s cast.
~ This is from back at the first of the year, but thank god. You can now relax and have as many of “god’s eggs” as you want, as they’ve finally been cleared by the “authorities.” Thanks to O Primitivo Ricardo for that one. Oh, saturated fat is still the devil incarnate. So, one down & one to go.
~ And back-to-back good stuff from Ricardo; this, an email I’ve had in my inbox for far to long. While he pointed me to a whole bunch of Japanese studies, I find the first one the most compelling.
The Relationship between Total Blood Cholesterol Levels and All-cause Mortality in Fukui City, and Meta-analysis of This Relationship in Japan
Shirasaki published a Japanese paper about the relationship between total cholesterol levels and all-cause mortality in Fukui City, Japan. His cholesterol data were not grouped according to ordinal 20mg⁄dL (0.52 mmol⁄L) intervals. In the present study, we re-calculated his data for meta-analysis. The relative risk (RR) of all-cause mortality adjusted for age and sex showed a decreasing trend with total cholesterol levels (p for trend <0.0001).
In order to summarize the relationship between total cholesterol and all-cause mortality, literature describing this relationship in Japan was collected mainly using computer search engines. Literature published before 1995 was excluded. Reports with the total number of study subjects smaller than 5,000 were also excluded. Five reports were found suitable for meta-analysis of cholesterol levels and all-cause mortality. Meta-analysis revealed that the RR in the <160 mg⁄dL (<4.14 mmol⁄L) group [RR=1.71 (1.41, 2.08)] was significantly higher than in the reference group [160-199 mg⁄dL (4.14-5.17 mmol⁄L)], and that the RRs in the 200-239 mg⁄dL (5.18-6.21 mmol⁄L) group [RRs=0.83 (0.74, 0.94)] and ≥240 mg⁄dL (≥6.22 mmol⁄L) group [0.78 (0.65, 0.95)] were significantly lower than in the reference group when both men and women were combined. We suggest that Japanese subjects with cholesterol levels ≥240 mg⁄dL (≥6.22 mmol⁄L) should not be regarded as hypercholesterolemic or dyslipidemic except when having some genetic disorders like familial hypercholesterolemia because they are in the safest ranges in terms of all-cause mortality.
We also have the full text PDF and here’s a very interesting excerpt.
However important the effect of cholesterol on CHD might be, the risk of all-cause mortality is lower at higher cholesterol levels. This is because of a very low incidence of CHD death in Japan (see introduction). Wether or not high cholesterol levels are a cause or effect of a high mortality, it is clinically very important to note that low cholesterol levels are associated to a sizable and significant extent with all-cause mortality (…)
Switching to LDL-cholesterol from the total cholesterol in the Guidelines is good because hypercholesterolemia due to high HDL-cholesterol levels can be excluded. At the same time, this switching is very confusing. There are very few epidemiological data about the relationship between LDL-cholesterol and deaths. Considering the present meta-analisis, JAS Guidelines appear to face a serious paradox. If a doctor prescribes cholesterol lowering medicines to subjects with cholesterol levels above 240 mg/dl (6.22 mmol/l), the doctor is prescribing medicines to those who have the least chance to die.
Those whose risk of death is smallest probably have the least need for medication. Japanese subjects with cholesterol levels above 240 mg/dl (6.22 mmol/dl) should not be regarded as hypercholesterolemic or dyslipidemic because they are in the safest ranges in terms of all-cause mortality except for some genetic disorders like FH cases. Further studies are warranted.