I've been razzing AHS a bit last couple of days. There was yesterday's post on Survival of the Richest, and you can see what sorts of stuff I've been putting out on Twitter with the #AHS14 hashtag. Yes: stuff that ought to be being addressed at AHS, but either isn't or is very underrepresented amongst what's basically about the same stuff 4 years running now.
This next story was sent to me by Karen Pendergrass, creator of various Paleo Movement initiatives.
Karen Pendergrass is the Author of Eat Paleo Save the World!; Founder and Executive Director of The Paleo Foundation, Certified Paleo, Paleo Approved, and Paleo-Friendly Food Certification Labels; creator of the International Paleo Movement Group on Facebook, and creator of The Paleo Movement Online Magazine.
She's given me permission to post it. Prepare to have your mind blown.
I sent this as a pm to Robb because I didn't want you to know that I respected you one iota... I try not to, but I can't help myself. On a personal level, I think you're an off-base prick who throws tantrums because nobody really checks you. On a professional level, I'm anxious for the book you're writing about the gut microbiome because it's been a huge area of interest for some time now.
Anyway, here's what I sent to Robb:
I went on a VLC diet for 3 months to "put out the fire" in 2011 (per Mat's suggestion) to normalize insulin, cool PCOS, and reduce my chronic inflammation (remember when I looked like a balloon?) and to lose the 50lbs that came out of thin air in 2009. My little experiment didn't work, in fact it backfired--my liver enzymes shot back up to danger zone, I still had glucose days regulation, PCOS, distention, and no change in weight.
Everyone, including myself, threw their hands in the air. But then I gained 9 lbs in a week on antibiotics and decided to research the shit out of why that happened to me, since I knew from previous studies that cows given subtherapeutic doses of antibiotics did the same, but I never asked why... Do you recall this email to you and Mat?
I learned a lot. My new experiment was to focus on gut normalization. I had a DIY, at-home fecal transplant, I went very high carb, high FOS diet for a week (jicama bender) and lo and behold... Loss of 25 lbs in one week. Oh, and I drank a metric fuck ton of orange juice after reading this awesome study about OJ and how it miraculously mitigates an inflammatory response after a high-fat meal. I fucking love OJ.
And much as I hate to agree with Nikoley here... I kind of have to. This is not to negate the clinical, either... This is to say those who are metabolically broken cannot—always—be fixed by carbohydrate limitation, and although this is a currently unfalsifiable hypothesis, I surmise that all people with metabolic conditions would be normalized faster if the focus was on gut normalization first, which may call for higher carbs and, god forbid, less meat. More than one way to skin a cat you know?
Now, I know I'm not the rule, I'm the exception. But even the exceptions must be taken into account when blanket prescriptions are made, like "when glucose regulation is an issue, limit carbs. DONE." No disrespect love, I find that to be somewhat specious given what we're learning about the gut microbiome.
And in light of the fact that some nasty, pathogenic, gram-neg groups (usually disproportionately high in T2D) produce 10x the LPS (if I recall correctly, let me double check) as other indigenous species, and how that effects hormonal fluctuations and, of course, glucose dysregulation/insulin resistance... Even red meat, in the presence of hypochloridia (as you know, it's also common) can exacerbate the condition if it's fermenting in the gut, breeding specific types of pathogenic bacteria while starving out the regulatory, colonic species.
At least, this explains my success on high-carb focus on FOS Paleo and no success on low carb Paleo.
She ads, to me:
"So that's it. If you want to see my studies/papers that got me to these conclusions I'm happy to share them. I might have some you don't have yet, I'm not sure. But they are awesome.
"If not, suck it easy."
I love straight-talkin' gals.