What Do You Think You Know About LDL Cholesterol? (Part One)
Are you aware that the LDL cholesterol results you get in your routine blood workup is likely a complete fiction? That's right, and it's because LDL isn't measured, but calculated. Here's the formula, called the Friedewald equation: LDL = Total Cholesterol - HDL - Triglycerides/5 So, for example, if one goes on a grain based, high carb, low fat diet which is well known to make triglycerides skyrocket, what would be the effect on your (calculated) LDL, all else remaining about equal? Your LDL would go down, your doctor would be pleased, you'd be ecstatic, and you may have actually increased your risk of, um, death (but maybe not of a heart attack, so yippee!). In fact, both very high and very low LDL associate with all-cause mortality (death from all cause, not just cherry picking heart disease). Where does risk appear to be lowest? I'm not sure, but for cancer risk, it's an LDL of around 130, i.e., lower or higher equals greater risk, and remember, I'm talking about LDL alone. So, you want to reduce your LDL like a good soldier? Then increase your triglycerides dramatically. All else remaining equal, each 5-point increase in Trigs gets you a...
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