After a period of reading another couple of books, I have just picked back up on Gary Taubes' Good Calories, Bad Calories once again over the last couple of days. You know what? This is an amazing work on general grounds. Taubes is a consummate and meticulous advocate of the scientific method; i.e., you first form a hypothesis and then do your honest, dead level best to refute it. To the extent you fail time after time, the hypothesis gets stronger and stronger because you are systematically eliminating everything that can be speculated to count against it. It's the only valid way to do science. You can't "confirm" a hypothesis in the sense of coming up with conditions under which it holds, for no matter if it holds under a million such conditions, you need but one to obliterate it. The depth and research into this book is amazing. No wonder it took five years to write. In a nutshell, you have the Ancel Keyes fat-cholesterol-heart hypothesis that just won't die, which is itself based upon his flawed Seven Countries Study. From the Wikipedia article: These studies found strong associations between the CVD rate of a population and average serum...