Not labeled as such, but here’s Part 1: PhD Physical Chemist Commenter Marie is at it Again! Resistant Starch and Ketosis. Low Carb in Short Pants. There, we learn that while trying to keep her dad in ketosis for cancer therapy while upping his food choices to keep him in the game, she initially had difficulty.
Why? Well, resistant starch supplementation does improve fasting blood glucose. That’s in the literature, and she duplicated it. It also blunts blood glucose spikes. That’s in the literature—also: “lentil effect,” “bean or legume effect,” “second meal effect,” etc.—too, but she was kinda only able to kinda duplicate that if V/0/LC and in ketosis.
Why? Here’s probably why, in my view: too very low carb, too ketogenic too often, too long. Simply stated, it wreaks havoc on the other 90% of you—your gut biome—and has downwind repercussions, such that VLC and ketogenic become solidly an intervention therapy (like for her dad’s cancer) and not a “healthy lifestyle.” Mind you: I have zero problem with the former. My beef is with the latter.
I have her data from back then and will publish it when I’m more sure I have more of everyone’s attention (it’s looking better and better by my secret metrics). But the “teezer” element is that after more time supplementing resistant starch via Bob’s Red Mill Potato Starch—that’s gonna set you back a whopping $13.50 for 96 ounces (6 pounds)—she actually had better results with a pure sugar carb load while in ketosis. Blunted by her flourishing gut, producing saturated fats (…that’s “SFCF,” for when you don’t want to get all LC/Paleo giddy about it and imply contradictions in your own thinking and conclusions. Thank God for SFCFs, so you don’t have to write “saturated fat” or “saturated, short chain fatty acids” when it might be “inconvenient.”)
Here’s how I ended yesterday’s post, quoting the lovely Marie:
Well, I did the test in fasted ketosis. Had changed plans for the weekend to stay fasted until this afternoon and of course have been looking at yogurt and honey rather than potato as the ‘challenge,’ food since that’s what dad misses most.
Now I feel like being une tease Gauloise (bien sûr!) so come on, before I tell you what happened, you tell me, what are your guesses?
Hint: BG effect was all over in 60 minutes, though I kept on testing ketostix until something interesting happened.
Now, here’s what happened; and, mind you, this is after several previous failed tests using resistant starch to blunt BG and remain in ketosis in the face of a starch/carb load. Here we go with Greek yogurt & honey which I guess is like Food of the Only Good Gods we Ever Had—the Greek ones.
The rise was just 18 points. It went from 83 to 101 mg/dl. 44hrs fasted. Took 2 Tbsp Bob’s Potato Starch (PS) in water during the fast (0 GL).
Then the meal : 2 Tbsp PS in water + 1 1/2 Cups Yogurt + 3 Tsp Honey.
Took BG every 15′ after end of meal.
- pre : 83
- 15′ : 92
- 30′ : 101 (peak)
- 45′ : 91
- 60′ : 80 (~baseline)
keept going, just in case :
- 75′ : 81
- 90′ : 81
- 105′: 82
- 120′: 80
Been keto-positive, purple, at “40” all day and right before meal. Eau de nail-salon was very evident.
- 75′ : still slightly positive, peach-pink, “5”. Likely due to ‘older’ part of excretion, before acetoacetate shut-off.
- 2 hrs : null, no color change.
- 3 hrs : null, no color change.
Technically, out of ketosis. Since false negatives are biochemically possible even with continual urine testing, would need blood ketone measurement to confirm. However, makes sense. Could have stopped here. But I didn’t. [This is the point. –Ed]
- 4.5 hrs : slightly positive, peach-pink “5” (since this can always be ‘vague’, keep going…)
- 6 hrs : yup, definitely pink-purple “15”.
- 7 hrs : pink-purple “15”.
I’m off to bed now. If I could stay up, we’d find when it goes deeper purple, 40, but who cares, effect was detected. Ketosis was recovered quite quickly. If I wake up at night like I sometimes do, I’ll check again.
So after 2+ months of taking PS, when now taking PS WITH the yogurt + honey I get only a small BG response EVEN in fasted ketosis, despite that state’s famous physiological insulin resistance.
This is also a controlled study, meaning we do know that physiological insulin resistance works in me too without PS, from earlier results under the same conditions.
Apparently, give me PS long enough and that resistance is much, much muted, to the point that the BG response is one of the lowest ever for this meal in any metabolic state (ketosis or not).
A tu aussi, Mariechérie. Bien merci.
Three words: This. Will. Continue. So much for: “it’ll knock you out of ketosis.” Make the most of technicalities, if you like. I’m giving it to you on a silver platter. So go ahead, make Big Waves.
…Final note. How many remember the name of my politics/social blog before I changed it to Free the Animal? From about 2005-2008, or so, its name was Honesty Log. From 2003 until then, it was Uncommon Sense.
Noticing any common thread?
Update: Just going in to delete all emails on this and there was one from Marie I hadn’t noticed before. She wanted to ensure that her final ketosis measurement was actually 7.5 hour, NOT 7 hours.